Serena Williams to Dozens of Stars: The list of celebrities who have chosen weight loss medication to achieve their transformation

Jameela Jamil Criticizes Celebrity Endorsement of Weight Loss Drugs, Responds to Serena Williams’ Announcement

After talking about Serena Williams’ recent decision to promote weight loss medications and describing it as an “unforced error,” Jameela Jamil had to clarify her position multiple times.
The Good Place star, while saying that her comments “absolutely not about Serena or her decision to do as she pleases with her body,” indicated that she was somewhat shocked by the disclosure of the 23-time Grand Slam champion that she lost 31 pounds with GLP-1 medication.
“Serena Williams is selling GLP-1s,” Jamil said on Instagram Aug. 24. “The thing I feel most uncomfortable about here is that celebrities have access to doctors most others don’t have access to. These so-called ‘miracle’ weight loss drugs come at a price.”

Jameela Jamil Warns of Serious Risks Linked to Celebrity-Endorsed Weight Loss Drugs

Jameela Jamil echoed her trepidations by talking about the possible harms that weight loss drugs may cause. The side effects mentioned can cover from the immobilization of the digestive system, the inflammation of the pancreas, to cancer, hair loss, osteoporosis, extreme lack of nutrition, loss of muscle mass, depression (among the symptoms of which suicide is spoken of), thyroid problems, blindness—and quite a few of them can slow down your metabolism severely,” she cautioned.
In addition, the 39-year-old also admitted that a lot of people who discontinue that medication “not merely re-gain the lost weight but they re-gain it within a very short time period.” She went on to say, “Medical support is what you need. In case something is not going well, you don’t have a billion dollars to fix it. That is the reason why I don’t like celebrities promoting drugs with such extreme side effects that are not even fully known.”

Jameela Jamil Insists on Openness in Celebrity Endorsements of Weight Loss Drugs

In the caption of her post, Jameela stated that people can do as they please with regard to taking weight loss drugs but she advised them to “make sure you have access to proper healthcare” if they were to contemplate such choices.
Moreover, she remarked that the husband of Serena Williams, Alexis Ohanian, is an investor in Ro—the company that Serena is referred to as promoting—a point supported by a Reuters report. Jameela referred to this as “just another reason to take celebrity endorsements with a grain of skepticism.”
The following day, the actress issued a statement that she was not intending to accuse Serena directly of doing what she did, rather she wanted to release a statement that said there should be more honesty with these kinds of endorsements and decisions.

Jameela Jamil Defends Serena Williams, Questions the Celebrities Taking a Ploy from the Weight Loss Industry

“Also, I wrote a long Substack supporting Serena’s absolute right to do with her body whatever she wanted,” Jameela explained on August 25. “Her body has been under surveillance in the past. It is not about her or her decision. It is about how celebrities are advertising drugs and diet products—full of glamour, no revelation of the little truths.”
Jameela commented on the misunderstanding of her words she referred to as “inaccurate reporting of what I said” by media, after her first article.
“I didn’t blame her for telling the truth about the drug,” Jameela clarified. “I even applaud the truthfulness. However, I have a problem with i… privileged celebrities turning to the fans caused by drugs with adverse effects when there is a lack of suitable healthcare for the rest of the population.”
Afterward, she explicitly mentioned, “I love Serena and would never throw shade at her or cancel her without good reason.”

A Growing Trend Among Celebrities

Though Jameela Jamil’s remarks highlighted Serena Williams’ employment of weight loss medicine, the sports icon is not the only one. The celebrities have become vocal about their use of Ozempic, Wegovy, and Mounjaro. Besides the conversation about health and weight loss, these stars have also talked about how they changed their bodies with the help of medication.

Rosie O’Donnell Opens Up About Weight Loss with Mounjaro

The comedian Rosie O’Donnell disclosed that she has been on Mounjaro which is an anti-diabetes type 2 drug, since the end of 2022. Her gradual change was made public by her Instagram post in which she flaunted her new figure that was visibly less.
Rosie wrote on her post, “I can not fathom this, it seems to me this is not me.” Among other hashtags like #mounjaro, #weightloss, and #bodydysmorphia, she used #bodydysmorphia to her post. Her honest revelation hit a chord with her audience and led to discussions about a recent trend of celebrity endorsements of GLP-1 drugs for weight control.

Meghan Trainor and Husband Daryl Sabara Work on Weight Loss as a Team

After the birth of their first child Riley in 2021, singer Meghan Trainor and her husband actor Daryl Sabara decided to work out as a team and set fitness goals. They initially did the 75 Hard challenge, with Meghan sharing her experience on their Workin’ On It podcast April 9 episode: “And, man, did we crush it.”
Not long after that, the couple motivated by their friends and doctors’ recommendations decided to take Mounjaro, beginning with the lowest dose. They complemented the injections with exercise and healthy meals. “Me and Daryl do everything together,” Meghan said. “And we took off on that path.”

Kendra Wilkinson Denies Shock Weight Loss Injection After Only One Dose

Once off The Girls Next Door Kendra Wilkinson revealed she only briefly used a weight loss injectable and quit almost immediately. “I did start the weight loss shots,” she said by way of explanation on Instagram Stories in April 2025. “Just went in for the shot once. No way. Absolutely throwing it away!!”
The ex-Playboy and mother of two explained that the reason for the change of mind was that the potential benefits would be far outweighed by the health concerns. “Had too many horror stories about the people around me,” Kendra went on. “People are in hospital, have operations. No, thanks.”

Nikki Glaser Defends Ozempic, Urges Openness Around Weight Loss Drugs

Comedian and Golden Globes host Nikki Glaser is fully on board with Ozempic without an iota of doubt. In her March 2025 interview at The Tonight Show, she demanded less stigma and more openness towards the drug.
“I’m totally on board with it. I’m like, ‘Get on with your bad self,’” Nikki said with energy. “I have zero judgment. If you want to do Ozempic, absolutely, girl.”
While doing so, she also mentioned that people who feel shame towards weight loss taking drugs may be coming from a wrong place of thinking. “Shame is really only from skinny folks who want to keep you fat,” she disclosed. “They’re so angry that you’re becoming thin now because that’s all they have left, right? You’re the one who is lively, with a great character, and they’re so angry.”

Brooks Nader Reveals Why She Stopped Using Ozempic

Brooks Nader, the model, confessed that she tried Ozempic once but decided to quit after getting on Dancing With the Stars in the fall of 2024.
“I basically did just a little bit when it was new, and everyone was jumping on the bandwagon,” she told Us Weekly in December 2024. “It made me very sick with nausea. I liked it – I will not lie – and when I was on DWTS, I was unable to do both.”
Brooks clarified that the drug made her less wanting to do physical exercise. “I lost a little bit of the motivation and the strength to work out,” she admitted. “It was one or the other, and I went for dancing. I put the shot away.”

Bonnie Chapman Attributes Tirzepatide to 58-Pound Weight Loss

Bonnie Chapman, the daughter of Dog the Bounty Hunter star Duane Chapman, announced on November 1 that she had lost 58 pounds in only 10 months. She credited her upheaval to both lifestyle changes and the employment of the weight loss drug Tirzepatide.
“I am able to see myself in the mirror and be so proud of the place where I’ve gotten,” Bonnie expressed.
Anyway, she had her share of obstacles. She was miserable with Ozempic before she aced Tirzepatide. “I really disliked it,” she confessed to E! News. “I could not eat without feeling sick. Sometimes I could not eat at all. My body was not comfortable with it.”

Jessel Taank Disavows Ozempic Usage, Attributes Her Glow-Up to Other Reasons

Real Housewives of New York City star Jessel Taank responded to the rumors about her between 14th and 15th seasons transformation, rejecting weight loss drug rumors with a prompt denial.
“I think it is so typical that being in the world of reality TV you instantly come to the conclusion ‘Oh, she got plastic surgery or she did that or she is on Ozempic,'” she said to Us Weekly in October 2024. “I really f–king hate Ozempic. I am definitely not the type of person that puts needles in myself.”

Lizzo Responds to Speculation About Ozempic Use

After Lizzo shared a video that featured her with less weight, she was quickly speculated about by social media users. Numerous fans came up with the idea that she might have taken Ozempic to get her figure.
Instead of outright confirming or denying, the Grammy-winning singer and rapper decided to use humor in the response to the rumors. She uploaded a TikTok clip with a popular Christoph Waltz’s character in Django Unchained saying, “It’s like a reward.”
Lizzo is a proponent of body positivity and has been quite outspoken about the negative critique that she and other female celebrities receive. She did not comment on the rumors, but her post was consistent with her typical approach of mixing humor with the portrayal of how the public reacts to changes.

Lottie Moss Calls Ozempic “the Worst Decision I Ever Made” After Health Scare

Lottie Moss, the younger sister of supermodel Kate Moss, shared a terrifying incident of Ozempic overdose that required her to visit the hospital, and she gave this information on her Dream On podcast in September 2024. She confessed the model that she made the mistake of using a dosage that was meant for those who weigh over 220 lbs when she was far below that weight, and she is now a regrettable decision of her life.
The results of it were very bad. Lottie said she very fast couldn’t even eat food or drink water, and so she got the emergency treatment. “I can remember that I passed out because I was so dehydrated, which to me was the scariest thing that has ever happened to me,” she said. “My friend had to hold my feet down. It was so scary, the whole situation. My face was clenching up, my whole body was tense.”
Her blunt perspective is a stark reality on using weight loss medications the wrong way and especially, if one is doing it without the guidance of a qualified doctor. Lottie, by telling her story, is in the company of other celebrities who are giving the same message while these drugs are still popular in the Hollywood area.

Jon Gosselin Credits Semaglutide for 32-Pound Weight Loss

The celebrity from Jon & Kate Plus 8, TLC, Jon Gosselin, said in April 2024 that he lost 32 pounds in two months when he went on semaglutide injections, which is the generic form of Ozempic. He disclosed the progress to Page Six during the interview, describing how it changed completely his situation.
“You know what’s annoying?” said Jon. “The regret of not doing it 10 years ago.”
Jon’s thoughts while celebrating his victory are reflective of a wider dialogue about how the availability and knowledge of weight loss drugs have changed significantly over the last few years, much because of the numerous public figures who have decided to disclose their personal experiences. The frank confession turned into another celebrity making an admission of using GLP-1 to aid weight loss and for a healthier lifestyle.

Ree Drummond Clears Up the Misunderstanding That She Lost 50 Pounds with Ozempic

Ree Drummond, The Pioneer Woman, announced on her blog in March 2024 that she was not only surprised by the rumors but also wanted to make it clear that she did not use Ozempic to lose 50 pounds in 2022. The change of her life was solely from her own power without any aid from weight loss drugs.
Ree however made it clear that she was not totally closed off towards people who might disagree with her. She said: “But you will never get from me even a millisecond of judgment about those who decide differently!” showing empathy for people who are brave enough to take the road less traveled when it comes to their health.”
Her sane take on the matter struck a chord with many of her followers as it acknowledged that the issue of weight loss is quite different, yet there is an important lesson of empathy in the big talk.

Tracy Morgan Shares About His Ozempic Voyage With Some Humor

In short, Tracy Morgan, the popular stand-up and 30 Rock alumnus, very openly and honestly told the public about his Ozempic voyage when he was a guest at Today With Hoda and Jenna in August 2023. He announced that the medicine was his savior in losing weight and explained that the way it was successful was by restricting his craving for food.
Still, as per usual with Tracy, he made a joke about it later. While promoting at Jimmy Fallon’s The Tonight Show in March 2024, he said jokingly, “I have figured out how to eat more than Ozempic. I put on 40 pounds.” His joke led to an avalanche of news stories and conjecture about his situation.
A bit later, as a response to the comments, Tracy shared a video of himself talking to the camera, saying, “My comment was meant as a joke.” “I really had a good time with Ozempic and I was happy to make use of it,” he went on to say, thereby indicating that the medicine was his ally in the fight against his health condition.

Caroline Stanbury Describes Ozempic as One of the “Best Tools” for Weight Loss in Midlife

The Real Housewives of Dubai star Caroline Stanbury that turning to Ozempic was a “midlife crisis” escape for her at 45. In her Uncut & Uncensored With Caroline Stanbury podcast episode on May 22, she shared her struggle with controlling weight in her 40s.
“We all know that it’s really, really hard after 40 to lose the weight,” Caroline said. “But I met so many 40-year-old women who were saying, ‘How did you manage to do it?’ And I don’t want to lie to you, I used Ozempic, which I consider one of the best tools if you can use it.’”
Caroline’s openness placed her among the celeb group who admit the use of weight loss drugs as part of their wellness path while confessing that issues of age and body have become the turning point of the discussion.

Jennifer Aydin Jokes About Her Weight Loss: “I’m on Mounjaro, Okay!”

A day after Jennifer Aydin refused to let rumors about her weight loss get the better of her, she appeared on Watch What Happens Live in July 2024 and once again put everything straight.
Before adding cheekily, “I’m on Mounjaro, okay. I’m sorry!” she said, “I am not on Ozempic.” Laughing, she went on to rave about how great she felt after taking the drug. “This is the weight I love being with; I swear if you can’t tell I am full of energy.”
Her forthright admission, made in jest, not only shone a light on the widespread use of weight loss drug injections among the Bravo stars but also gave them the impression of a confidence and vigor revival when they decide to use them.

Kandi Burruss Opens Up About Her Struggles with Weight Loss Injections

Former Real Housewives of Atlanta star Kandi Burruss shared the truth about her injectable weight loss journey when she confessed during a June 2024 interview that the therapy just wasn’t her “go-to” solution.
“It did not happen to me to be the agent that it was to calm down my hunger,” said Kandi. “Some folks say they cannot eat at all, while I am the exact opposite! I was eating an appetizer, a full meal, and even dessert, are you getting me? Nothing was interrupted by the injection for me.”
She added the emotional impact she experienced due to lack of progress. “When you are watching it turned out effective in others and not for you, it makes you downcast,” Kandi reminisced. “Honestly, it makes one think, ‘What is wrong with me? Why is it that it is not working for me?’”
Her candid confession emphasizes that weight loss injection is not the same for everyone as they can have very different outcomes in different people.

Brooke Burke Offers Her Viewpoint On The Advantages And Disadvantages Of Ozempic

The TV celebrity and a fitness lover Brooke Burke, not long ago, gave her input to the increasing trend of the Ozempic topic. In her interview with Fox News Digital, she conceded that she was not a doctor but still recognized the complexity of the ongoing debate.
“I am not a doctor and hence I can’t speak medically about it, but in my opinion, there is so much info about what is working and what is not,” Brooke explained. “I guess that Ozempic can bring some good advantages to people, and at the same time, I think that it also carries some risks.”
Her mood was more or less the same as most opinions about weight loss drugs. While some users were delighted with the effects, a few were anxious about the possible side effects and safety in the long run.

Jade Thirlwall Admits Avoiding Ozempic Is a “Daily Battle” Given Her History with Eating Disorders

Jade Thirlwall, former member of the chart-topping girl group Little Mix, has long been candid about her past struggles with anorexia. In an August 2025 interview with The Guardian, she revealed that the rise of Ozempic and similar weight loss medications has posed a unique challenge for her.

“I have a daily battle with myself not to go on Ozempic,” Jade admitted. “I don’t judge people that do, but because I have a history of eating disorders, I don’t know where taking something like that would end for me.”

Her honest reflection highlights an important perspective often missing from the broader conversation: while weight loss drugs may offer benefits for some, they can also be triggering and potentially harmful for those with a history of disordered eating. Jade’s transparency adds depth to the growing dialogue around the cultural pressure to stay thin and how individuals navigate those choices differently.

Tori Spelling Reveals Mounjaro Worked After Ozempic Failed to Deliver Results

The amazing Tori Spelling, actress, and one of the saccharine celebrities of Beverly Hills, 90210, commented on her lengthy postnatal weight loss journey after the birth of Beau in 2017. In the April 2024 episode of her misSPELLING podcast, she reported that she was not satisfied with the outcome of Ozempic and that eventually, she had to reject it.
“I was on Ozempic but the result was zero, for me,” Tori said. “After that, I was allowed to take Mounjaro, which put me in the right track and I did shed pounds.”
Her open acknowledgment highlights how the effectiveness of weight loss injections can significantly differ, revealing that some patients can barely get positive results with one drug and then have a significant breakthrough on another. Tori’s testimonial is one of many that indicate the celebrities’ journey through the ups and downs of their makeover process.

Raven-Symoné Emphasizes the Dangers of Misusing Prescription Medications

Raven-Symoné conveys the significance of the proper use of prescription drugs. Among her recent statements is the one to E! News’ Francesca Amiker, where the actress maintained that health gadgets should be the last resort for treating diseases as well as being the source for health, as well as the beauty or lifestyle industry.
“It is very necessary that we realize that certain drugs are specifically designed for certain individuals,” said Raven-Symoné. “Do whatever you feel like but medications should be kept for those who really need them.”

Sharon Osbourne Opens Up About Weight Loss with Ozempic

The Talk U.K. presenter, Sharon Osbourne, announced her weight loss via Ozempic in June 2023 and in September she admitted that her weight loss journey with the medication was a success as she lost 42 lbs.
“Whatever works for you is fine with me,” Osbourne said to E! News. “It’s not a surprise if you do something to help you lose weight and that it’s okay.”
Furthermore, she mentioned that it is nice to be truthful, saying, “We don’t have to act.”

Kelly Osbourne Praises Ozempic for Weight Loss

Kelly Osbourne has shared her view about the trend of using Ozempic to help lose weight.
” In my opinion, it is a fantastic thing,” the Fashion Police alum told E! News in January 2024. Along with that she said, “There are countless methods to get rid of extra weight, why not choosing one that is not as dull as exercising?”

Kate Winslet Opposes Weight Loss Drug Trend

While a number of stars are getting ready to embrace the use of injectable drugs, Kate Winslet has a different opinion. In a March 2024 interview with The New York Times Magazine, the Titanic actress said she was quite a stranger to Ozempic but went on to express a safety concern after she got acquainted with it.
“I simply do not know what Ozempic is,” Winslet confessed, at first assuming it to be a tablet. Upon being told that it was a shot, she became less than thrilled: “Wow. This could be the last thing I’d want to hear.”

Heidi Montag Declines Ozempic, Focuses on Hard Work

Heidi Montag is not associating her name with the popular celebrity weight loss trend that is Ozempic. In December 2023, the Hills ex-girl-next-door confided that she had lost 22 lbs in a short time and emphasized that she had achieved it without the injectable drug.
“No shortcuts in life. And if you are using that shortcut, I don’t know,” Montag said to Page Six, indicating that the route was not hers. “I am not the one to drop names or dig into that, it’s just not something that I would do,”
She stated that her attention was on health and staying with it. “I want something that is doable,” Montag stated. “I want something that also necessitates hard work.”

Amy Schumer Calls for Honesty in Ozempic Conversations

Not shying away Amy Schumer position is the fact that Hollywood is more than willing to welcome Ozempic usage. On June 8, 2023, during her appearance on Watch What Happens Live, she sarcastically accuses celebrities of deceit by picturing the use of the weight loss drug along with light and undefined lifestyle changes.
“Sooner or later everybody and even their mother are going to do it. Everyone has been lying saying: ‘Oh, we are cutting the size of the portions,’” Schumer told Andy Cohen. “Actually, say nothing. You are on Ozempic or one of those drugs, or you had surgery. Just don’t talk.”
“People need to be honest,” said Schumer, who has been candid about her own plastic surgery. “I got lipo, I said I got lipo,” she added.
She also disclosed she only took Ozempic once, and that was in 2022. However, the side effects made her unable to perform as a mother to her small son, Gene. “I was one of those people that felt so bad that I couldn’t do the things with my son that I wanted,” she said. “I was so thin, and he’s throwing a ball at me and I couldn’t.”

Dr. Drew Pinsky says that Ozempic shouldn’t be stigmatized

Celebrity physician Dr. Drew Pinsky is stepping in with his opinion amidst the debate surrounding Ozempic and similar drugs. In his exclusive statement to E! News at Fox’s Special Forces: World’s Toughest Test event in L.A. on Sept. 12, 2023, he referred to the public’s contradictory views regarding the use of medical drugs.
“People are in two minds about medical interventions such as this,” Pinsky said. “They are intrigued by it, but at the same time, they bring in this odd judgment.”
The TV doctor of many years fame, also remarked that diabetes injections like Ozempic could be a breakthrough if handled correctly. “The moment we have a drug that can bring relief to the problem, then yes, the people should be advised to consider it,” he added.

Sophie Turner Slams Ozempic Ads in Times Square

Sophie Turner is sharing the details of how she feels about the promotion of Ozempic. The Game of Thrones alum, as usual, outspoken but this time in a negative manner, threw the ads for weight loss a sharp jab in April 2023.
Turner, on her Instagram Story, shared a tweet by writer Sophie Vershbow who was not only sharing but also relating the photos she took of Ozempic ads that were spread across the Times Square subway station. The posters were advertising with slogans like “One shot to lose weight” and “A weekly shot to lose weight.” Vershbow wrote, “The f–k the Ozempic ads plastered across the Times Square subway station can go,” to which Turner responded, “WTF.”
In response to the escalating criticism, Novo Nordisk, the company behind the drug, stated to E! News that Ozempic is not approved by the Food and Drug Administration for the treatment of chronic weight management. The company acknowledged that some doctors might off-label prescribe the drug for weight loss but stated that Novo Nordisk “does not promote, suggest, or encourage” that use and is committed to abiding by U.S. laws and regulations.

Chelsea Handler Discloses That She Was Given a Prescription for Ozempic Without Her Knowledge

Chelsea Handler claims that she was given a prescription for Ozempic without her knowledge. The comedian shared on the Jan. 25, 2023 episode of the Call Her Daddy podcast that her “anti-aging doctor” recommended the drug as a casual way to shed a few pounds.
“I didn’t even know that I was on it,” Handler elaborated. “She said, ‘If you want to get rid of 5 lbs., there’s nothing better than this.’
Handler remembered that after coming back from vacation, she was in a weird mood and when she injected the medication into herself she felt that way too. “We went to lunch, a girlfriend and I, a few days later, and she said she was very little eating, she was going to be very nauseous because she was on Ozempic, and I was ‘I also feel a little sick’,’ she recollected.
Handler ultimately chose to discontinue the drug and decided that it was not for her. through this, she gave the reason that she was not sick only, so she did not throw the remaining doses in the trash but rather gave them away. “I’ve done about four or five injections of my friends with Ozempic because that’s when I realized that it was silly to do it and that’s why I’ve done it”, she said. “people with higher weight”

Khloé Kardashian Denies Ozempic Speculation

That’s not true say Khloé Kardashian. Her slim figure is due to hard work and dedication in the gym, not weight loss medication she argues. Following comments on her Instagram last month in which it was suggested that she might be on Ozempic, the reality star upset the apple cart with her statement of results from personal training.
“Do not lower my years of training,” wrote Kardashian back. “Five days a week I train at 6 a.m. Stop with your assumptions. I suppose that a new year still means mean people.”

Dr. Terry Dubrow Experimented with Mounjaro to Comprehend Patient Experience Better

Plastic surgeon and reality TV personality Dr. Terry Dubrow, quite frankly, said he tried Mounjaro, a drug that has similar effects to Ozempic, only to find out how fast it works. In January 2023, the Botched doctor told E! News he briefly took the injectable only for his own curiosity and not because of any diabetes or severe weight loss.
Dubro added, “I thought it was great. I didn’t have that much weight to lose. The reason I wanted to try it was that so many of my patients were taking it, and I wanted to feel what it was like if you were not diabetic and had just 10 to 15 pounds to lose.”
Despite not disclosing the exact amount of weight he lost or the duration of his treatment, Dubrow stated that he is no longer using the drug. “I kept thinking, ‘You know, I actually would like to have my appetite back,’” he remarked, attributing the decision to stop the medication to experiencing “low-grade nausea” among other minor side effects.

Kyle Richards Denies Using Ozempic Amid Weight Loss Speculation

Kyle Richards is rejecting rumors about her recent weight loss with a lot of energy. The Real Housewives of Beverly Hills actress took to social media to address the speculation that she might be using Ozempic after several followers noticed changes in her appearance.
On Jan. 5, 2023, beneath her Instagram/selfie-with-friends-after-workout, Richards confirmed to a fan, “I am NOT on Ozempic.” She moved over to another comment and wrote, “I guess if anyone thinks I am on Ozempic, they are dead wrong. I have never been.”
On January 16, 2023, Richards restated her position after Page Six introduced the topic on Instagram, again denying, “I’m not on the medication.”